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PHERGAIN

OFFICIAL TITLE: CHEMOTHERAPY-FREE TRASTUZUMAB AND PERTUZUMAB IN HER2-POSITIVE (HUMAN EPIDERMAL RECEPTOR) BREAST CANCER: FDG-PET RESPONSE-ADAPTED STRATEGY. THE PHERGAIN STUDY

CLINICAL TRIAL DETAILS

THE STUDY ASSESS THE EARLY METABOLIC EFFECTS OF NEOADJUVANT TREATMENT WITH TRASTUZUMAB AND PERTUZUMAB (± ENDOCRINE THERAPY) ON THE PRIMARY TUMOR AND AXILLARY LYMPH NODES AND THEIR PREDICTIVE VALUE FOR PATHOLOGIC COMPLETE RESPONSE (PCR) IN THE BREAST AND AXILLA.
 
AND ALSO ASSESS 3-YEAR INVASIVE DISEASE-FREE SURVIVAL (IDFS) IN PATIENTS WITH HER2-POSITIVE (HER: HUMAN EPIDERMAL RECEPTOR) BREAST CANCER TREATED WITH NEOADJUVANT TRASTUZUMAB AND PERTUZUMAB (± ENDOCRINE THERAPY) USING A FDG-PET RESPONSE-ADAPTED STRATEGY.


PHERGAIN AT CLINICALTRIALS.GOV

TUMOR TYPE

PHASE

HER2+ EBC

II

377

56

Spain, Portugal, France, UK, Italia, Belgium, Germany

N

SITES

COUNTRY

STATUS

Analysis

PRESS RELEASE

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SCIENTIFIC IMPACT

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ESMO 2023 - HER2DX PHERGain substudy – DOWNLOAD THE POSTER

ESMO 2023 – HER2DX PHERGain substudy DOWNLOAD THE LAY LANGUAGE SUMMARY

ESMO 2023 –  Trop-2 PHERGain substudy – DOWNLOAD THE POSTER

ESMO 2023 – Trop-2 PHERGain substudy – DOWNLOAD THE LAY LANGUAGE SUMMARY

PHERGAIN CASE STUDY 2023 – DOWNLOAD

ESMO BREAST 2022 – DOWNLOAD THE SLIDES

SABCS 2017 – DOWNLOAD THE POSTER

Dr. Antonio Llombart highlighted the importance of translational studies within the PHERGain at ESMO 2023.

Dr. María Gion discusses the importance of biomarkers like Trop-2 in PHERGain's translational studies during the ESMO congress.

Dr. Cortes and Dr. Llombart PHERain interview
Beyond Chemotherapy
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Dr. Vanes Quiroga
Dr. Sofia Braga
Dr. Silvi Antolín
Dr. Escrivá de Romaní
Dr. Philipp Aftimos
Dr. Manuel Ruiz
Prof. Daniele Generali PHEGain interview
Dr. Jacques Medioni
Dr. Dunca Wheatley

Don't miss exclusive interviews with the principal investigators of the groundbreaking PHERGain study.

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PHERGAIN SITES

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Countries: Spain, Portugal, France, UK, Italia, Belgium, Germany

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