ATRACTIB
OFFICIAL TITLE: PHASE II CLINICAL TRIAL TO EVALUATE THE EFFICACY AND SAFETY OF FIRST LINE ATEZOLIZUMAB IN COMBINATION WITH PACLITAXEL AND BEVACIZUMAB IN PATIENTS WITH ADVANCED OR METASTATIC TRIPLE-NEGATIVE BREAST CANCER
CLINICAL TRIAL DETAILS
THIS IS A MULTICENTRE, OPEN-LABEL, SINGLE-ARM, PHASE II CLINICAL TRIAL. MEN AND WOMEN AGE ≥ 18 YEARS WITH PREVIOUSLY UNTREATED UNRESECTABLE LOCALLY ADVANCED OR METASTATIC TRIPLE-NEGATIVE BREAST CANCER (TNBC) THAT IS NOT AMENABLE TO RESECTION WITH CURATIVE INTENT. PATIENTS IN THIS SINGLE-ARM STUDY (N=100) WILL RECEIVE TREATMENT (INTRAVENOUS INFUSION) WITH ATEZOLIZUMAB IN COMBINATION WITH PACLITAXEL AND BEVACIZUMAB.
THE MAIN OBJECTIVE IS TO EVALUATE THE EFFICACY –IN TERMS OF PROGRESSION-FREE SURVIVAL (PFS)– OF FIRST LINE ATEZOLIZUMAB IN COMBINATION WITH PACLITAXEL AND BEVACIZUMAB IN PATIENTS WITH UNRESECTABLE LOCALLY ADVANCED OR METASTATIC TNBC.
TUMOR TYPE
PHASE
Breast
II
100
26
Spain, Italy, France, Germany and UK
N
SITES
COUNTRY
STATUS
Analysis
PRESS RELEASE
SCIENTIFIC IMPACT
SABCS 2023 – DOWNLOAD THE PRESENTATION
SABCS 2023 – DOWNLOAD THE POSTER
SABCS 2023 – DOWNLOAD THE LAY LANGUAGE SUMMARY
ASCO 2022 – DOWNLOAD THE POSTER
ESMO BREAST 2022 – DOWNLOAD THE POSTER
TRIAL RESUME
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Medizinische Fakultät Mannheim der Universität Heidelberg Frauenklinik
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Hospital Universitario Virgen del Rocío
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Complejo Hospitalario Ruber Juan Bravo
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Hospital Universitari Sant Joan de Reus
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Hospital Universitario San Juan de Alicante
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Hospital Universitario La Ribera
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Hospital Quirónsalud Valencia
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Hospital Universitario Insular de Gran Canaria
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Hospital Universitario San Cecilio
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Istituto Oncologico Veneto IRCCS
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IRCCS - Istituto Nazionale dei Tumori Fondazione "G. Pascale"
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Royal Cornwall Hospital - NHS Trust